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Pregnyl / Gonadotropin / HCG Pregnyl, gonadotropin, vials. Each Pregnyl vial contains 2500 IU gonadotropin. Together with each vial comes also one vial of solvent. Pregnyl comes in packs of three vials (+ three vials of solvent) and is manufactured by Farma Lepori. Description: HCG is provided as a glycoprotein powder to be diluted with water, and acts in the body like LH, stimulating the testes to produce testosterone even when natural LH is not present or is deficient. It therefore is useful for maintaining testosterone production and/or testicle size during a steroid cycle. Use of this drug in the taper is rather counterproductive, since the resulting increased testosterone production is itself inhibitory to the hypothalamus and pituitary, delaying recovery. Thus, if this drug is used, it is preferably used during the cycle itself. A daily amount of 500 IU is generally sufficient, and in my opinion usage should not exceed 1000 IU per day.Daily administration is superior to less frequent administration.Doses over 1000 IU are noted for their tendency to cause or aggravate gynecomastia, and also act to desensitize the testicles to LH.HCG may be injected intramuscularly, subcutaneously, or in a shallow injection about 1/4" deep with the needle going straight in. A 29 gauge insulin needle is recommended. Injection speed should be slow. HCG, or Human chorionic gonadotropin , which is derived from the urine of pregnant women, is an injectable drug available commercially in the United States as well as many other countries. Pregnyl , made by Organon, and Profasi, made by Serono, are FDA approved for the treatment of undescended testicles in very young boys, hypogonadism (underproduction of testosterone) and as a fertility drug used to aid in inducing ovulation in women. Among athletes, HCG is used to stimulate natural testosterone production during or after a steroid cycle which has caused natural levels to be reduced. Stopping a steroid cycle abruptly, especially when endogenous androgens are absent, can cause a rapid loss in the athlete's newly acquired muscle. When HCG is used to stimulate natural production, a notably pronounced crash may be avoided. HCG is always packaged in 2 different vials,one with a powder and the other with a sterile solvent. These vials need to be mixed before injecting, and refrigerated should any be left for later use. Common uses and directions for Pregnyl, gonadotropin: Pregnyl is an injectable, highly purified preparation of human chorionic gonadotropin obtained from the urine of pregnant women. Pregnyl is used in the treatment of prepubertal cryptorchidism not due to anatomical obstruction. Pregnyl is also used in selected cases of hypogonadotropic hypogonadism in males as well as for induction of ovulation and pregnancy in infertile women. Human Chorionic Gonadotropin, HCG, is also widely used in athletics today. HCG is not a natural male hormone but mimics the natural hormone LH (Luetinising Hormone) almost identically. LH stimulates the production of testosterone by the testis in males. Thus HCG sends the same message which results in increased testosterone production by the testis due to the effect of HCG on the leydig cells of the testis. Athletes use HCG to increase the body's own natural production of testosterone which is often depressed by long term steroid use. Dosage: Average dose is 1 ampule per week at the end of the cycle. Overdose: There have been no cases of overdose complications with the use of HCG nor have there been any associated carcinomas, liver or renal impairment. Additional information: Keep Pregnyl in a tightly closed container and out of reach of children. Pregnyl must be refrigerated after it is mixed together whereafter Pregnyl has a life of about 10 weeks.